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<title>Gideon Rodan</title>

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<h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Gideon Rodan</span></h1>

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<p><b>Gideon Alfred Rodan</b> (* <a href="14._Juni" title="14. Juni">14. Juni</a> <a href="1934" title="1934">1934</a> in <a href="Bukarest" title="Bukarest">Bukarest</a>; † <a href="1._Januar" title="1. Januar">1. Januar</a> <a href="2006" title="2006">2006</a> in <a href="Bryn_Mawr_(Pennsylvania)" title="Bryn Mawr (Pennsylvania)">Bryn Mawr</a>, <a href="Pennsylvania" title="Pennsylvania">Pennsylvania</a>) war ein <a href="Vereinigte_Staaten" title="Vereinigte Staaten">US-amerikanischer</a> <a href="Biochemie" title="Biochemie">Biochemiker</a> und Spezialist für Knochenstoffwechsel.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>

</p><p>Rodan studierte an der <i>Hebräischen Universität</i> in <a href="Jerusalem" title="Jerusalem">Jerusalem</a> und am <i>Weizmann Institut für Wissenschaft</i> in <a href="Rehovot" class="mw-redirect" title="Rehovot">Rehovot</a>, <a href="Israel" title="Israel">Israel</a>.

</p><p>Er untersuchte die Verformung von Knochenzellen. Seine bedeutendsten Arbeiten analysieren <a href="Osteoporose" title="Osteoporose">Osteoporose</a> und <a href="Knochenschwund" class="mw-redirect" title="Knochenschwund">Knochenschwund</a>. Dr. Rodan untersuchte die Verbindung zwischen <a href="Osteoblasten" class="mw-redirect" title="Osteoblasten">Osteoblasten</a> (Knochenzellen) und <a href="Osteoklasten" class="mw-redirect" title="Osteoklasten">Osteoklasten</a> (Calciumzellen), und half, beide Typen zu analysieren und zu beschreiben. Er und sein Team fanden heraus, dass eine Balance zwischen beiden Arten besteht.

</p><p>In den 1990er Jahren half Rodan, inzwischen Direktor der Abteilung für Knochenbiologie und <a href="Osteoporose" title="Osteoporose">Osteoporose</a> an den <i>Merck Research Laboratories</i>, einen Kompound, Fosamax, zu formulieren, der Osteoklasten hemmt und Knochenbrüchigkeit vermindert.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup>

</p><p>In weiteren Arbeiten untersuchte Rodan die Funktion von <a href="Steroide" title="Steroide">Steroiden</a> im Knochenmetabolismus und den Weg auf dem Knochenzellen mit <a href="Hormon" title="Hormon">Hormonen</a> kommunizieren.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Von 1970 bis 1985 lehrte er an der Universität an der <i>Schule für Zahnmedizin</i> in <a href="Connecticut" title="Connecticut">Connecticut</a>, wo er die Abteilung für Oralbiologie leitete. Später wechselte er zum Merck, 2003 emeritierte er.<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup>

</p><p>1987 wurde Rodan Präsident der <i>Amerikanischen Gesellschaft für Knochen- und Mineralienforschung</i>. Von 2001 bis 2003 war er Präsident der <i>Internationalen Knochen- und Mineraliengesellschaft</i>. Er war Herausgeber des Buches <i>Principles of Bone Biology</i> (1996).

</p><p>Rodan starb Neujahr 2006 an Krebs. Er hinterließ seine Ehefrau, ebenfalls Biochemikerin bei Merck, und zwei Kinder.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup>

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<div class="mw-heading mw-heading2"><h2 id="Literatur">Literatur</h2></div>

<ul><li>Jeremy Pearce: <cite style="font-style:italic">Gideon Rodan, 71, Scientist Who Researched Bone Loss</cite>. In: <cite style="font-style:italic">The New York Times</cite>. 20. Januar 2006 (<a rel="nofollow" class="external text" href="https://www.nytimes.com/2006/01/20/obituaries/us/gideon-rodan-71-scientist-who-researched-bone-loss.html">nytimes.com</a>).<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rfr_id=info:sid/de.wikipedia.org:Gideon+Rodan&rft.atitle=Gideon+Rodan%2C+71%2C+Scientist+Who+Researched+Bone+Loss&rft.au=Jeremy+Pearce&rft.btitle=The+New+York+Times&rft.date=2006-01-20&rft.genre=book" style="display:none"> </span></li></ul>

<div class="mw-heading mw-heading2"><h2 id="Einzelnachweise">Einzelnachweise</h2></div>

<li id="cite_note-1"><span class="mw-cite-backlink"><a href="#cite_ref-1">↑</a></span> <span class="reference-text">Lawrence G Raisz, John P Bilezikian, Michael Rosenblatt, Thomas John Martin, Masaki Noda, Dwight Towler, John Eisman: <cite style="font-style:italic">Gideon Rodan 1934–2006*</cite>. In: <cite style="font-style:italic">Journal of Bone and Mineral Research</cite>. <span style="white-space:nowrap">Band<span style="display:inline-block;width:.2em"> </span>21</span>, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>7</span>, 1. Juli 2006, <a href="Internationale_Standardnummer_f%C3%BCr_fortlaufende_Sammelwerke" title="Internationale Standardnummer für fortlaufende Sammelwerke">ISSN</a> <span style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://zdb-katalog.de/list.xhtml?t=iss%3D%220884-0431%22&key=cql">0884-0431</a></span>, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>979–983</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1359/jbmr.060700">10.1359/jbmr.060700</a></span> (<a rel="nofollow" class="external text" href="https://academic.oup.com/jbmr/article-abstract/21/7/979/7593185">oup.com</a> [abgerufen am 22. März 2025]).<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:Gideon+Rodan&rft.atitle=Gideon+Rodan+1934-2006%2A&rft.au=Lawrence+G+Raisz%2C+John+P+Bilezikian%2C+Michael+Rosenblatt%2C+...&rft.date=2006-07-01&rft.doi=10.1359%2Fjbmr.060700&rft.genre=journal&rft.issn=0884-0431&rft.issue=7&rft.jtitle=Journal+of+Bone+and+Mineral+Research&rft.pages=979-983&rft.volume=21" style="display:none"> </span></span>

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<li id="cite_note-2"><span class="mw-cite-backlink"><a href="#cite_ref-2">↑</a></span> <span class="reference-text">Gideon A. Rodan, Alfred A. Reszka: <cite style="font-style:italic">Bisphosphonate mechanism of action</cite>. In: <cite style="font-style:italic">Current Molecular Medicine</cite>. <span style="white-space:nowrap">Band<span style="display:inline-block;width:.2em"> </span>2</span>, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>6</span>, September 2002, <a href="Internationale_Standardnummer_f%C3%BCr_fortlaufende_Sammelwerke" title="Internationale Standardnummer für fortlaufende Sammelwerke">ISSN</a> <span style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://zdb-katalog.de/list.xhtml?t=iss%3D%221566-5240%22&key=cql">1566-5240</a></span>, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>571–577</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.2174/1566524023362104">10.2174/1566524023362104</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/12243249?dopt=Abstract">PMID 12243249</a> (<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12243249">nih.gov</a> [abgerufen am 22. März 2025]).<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:Gideon+Rodan&rft.atitle=Bisphosphonate+mechanism+of+action&rft.au=Gideon+A.+Rodan%2C+Alfred+A.+Reszka&rft.date=2002-09&rft.doi=10.2174%2F1566524023362104&rft.genre=journal&rft.issn=1566-5240&rft.issue=6&rft.jtitle=Current+Molecular+Medicine&rft.pages=571-577&rft.pmid=12243249&rft.volume=2" style="display:none"> </span></span>

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<li id="cite_note-3"><span class="mw-cite-backlink"><a href="#cite_ref-3">↑</a></span> <span class="reference-text"><span class="cite"><a rel="nofollow" class="external text" href="http://web.archive.org/web/20230219011152/https://www.researchgate.net/scientific-contributions/Gideon-A-Rodan-38590230"><i>Gideon A. Rodan's research works | Beth Israel Deaconess Medical Center, Boston (BIDMC) and other places.</i></a> Archiviert vom <style data-mw-deduplicate="TemplateStyles:r250917974">

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</style><span class="dewiki-iconexternal"><a class="external text" href="https://redirecter.toolforge.org/?url=https%3A%2F%2Fwww.researchgate.net%2Fscientific-contributions%2FGideon-A-Rodan-38590230">Original</a></span> am <span style="white-space:nowrap;">19. Februar 2023</span><span>;</span><span class="Abrufdatum"> abgerufen am 22. März 2025</span> (englisch).</span><span style="display: none;" class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2Fde.wikipedia.org%3AGideon+Rodan&rft.title=Gideon+A.+Rodan%27s+research+works+%7C+Beth+Israel+Deaconess+Medical+Center%2C+Boston+%28BIDMC%29+and+other+places&rft.description=Gideon+A.+Rodan%27s+research+works+%7C+Beth+Israel+Deaconess+Medical+Center%2C+Boston+%28BIDMC%29+and+other+places&rft.identifier=http%3A%2F%2Fweb.archive.org%2Fweb%2F20230219011152%2Fhttps%3A%2F%2Fwww.researchgate.net%2Fscientific-contributions%2FGideon-A-Rodan-38590230&rft.source=https://www.researchgate.net/scientific-contributions/Gideon-A-Rodan-38590230&rft.language=en"> </span></span>

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<li id="cite_note-4"><span class="mw-cite-backlink"><a href="#cite_ref-4">↑</a></span> <span class="reference-text">Lawrence G Raisz, John P Bilezikian, Michael Rosenblatt, Thomas John Martin, Masaki Noda, Dwight Towler, John Eisman: <cite style="font-style:italic">Gideon Rodan 1934–2006</cite>. In: <cite style="font-style:italic">Journal of Bone and Mineral Research</cite>. Volume 21, Issue 7. Oxford University Press, 1. Juli 2006, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>979–983</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1359/jbmr.060700">10.1359/jbmr.060700</a></span>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:Gideon+Rodan&rft.atitle=Gideon+Rodan+1934-2006&rft.au=Lawrence+G+Raisz%2C+John+P+Bilezikian%2C+Michael+Rosenblatt%2C+...&rft.date=2006-07-01&rft.doi=10.1359%2Fjbmr.060700&rft.genre=journal&rft.issue=Issue+7&rft.jtitle=Journal+of+Bone+and+Mineral+Research&rft.pages=979-983&rft.pub=Oxford+University+Press&rft.volume=Volume+21" style="display:none"> </span></span>

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<li id="cite_note-5"><span class="mw-cite-backlink"><a href="#cite_ref-5">↑</a></span> <span class="reference-text">Ivan Oransky: <cite style="font-style:italic">Gideon Rodan</cite>. In: <cite style="font-style:italic"><a href="The_Lancet" title="The Lancet">The Lancet</a></cite>. <span style="white-space:nowrap">Band<span style="display:inline-block;width:.2em"> </span>367</span>, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>9511</span>, 2006, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>644</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1016/S0140-6736%2806%2968249-4">10.1016/S0140-6736(06)68249-4</a></span>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:Gideon+Rodan&rft.atitle=Gideon+Rodan&rft.au=Ivan+Oransky&rft.date=2006&rft.doi=10.1016%2FS0140-6736%2806%2968249-4&rft.genre=journal&rft.issue=9511&rft.jtitle=The+Lancet&rft.pages=644&rft.volume=367" style="display:none"> </span></span>

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Normdaten (Person): <a href="Library_of_Congress_Control_Number" title="Library of Congress Control Number">LCCN</a>: <span class="-print"><a rel="nofollow" class="external text" href="https://id.loc.gov/authorities/n86076607">n86076607</a></span> | <a href="Virtual_International_Authority_File" title="Virtual International Authority File">VIAF</a>: <span class="-print"><a rel="nofollow" class="external text" href="https://viaf.org/viaf/71629657/">71629657</a></span> | </div>

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